Maybe a few more details from you about what security you have installed etc and is your system as far up to date as possible seeing as VISTA died a long time ago.
This issue is more specific to VISTA and might not be an actual Arduino issue.
As a possible fix you could disconnect as many USB items as possible and then in device manager delete the USB root hubs including driver if it offers that option.
Then a restart and wait for it to pick up what it needs for drivers.
While not specific to your device this may be worth exploring.