Error in uploading to board (Arduino Uno)

Hello. I am new to using arduino. I made a sun tracking solar panel, and the code worked fine. Now, I've been attempting to utilize Blynk with my sun tracker. In this process, after being able to upload code to my arduino uno perfectly well for weeks, I am getting the error code below.

Arduino: 1.8.7 (Mac OS X), Board: "Arduino/Genuino Uno"

Sketch uses 13548 bytes (42%) of program storage space. Maximum is 32256 bytes.
Global variables use 597 bytes (29%) of dynamic memory, leaving 1451 bytes for local variables. Maximum is 2048 bytes.
avrdude: ser_open(): can't open device "/dev/cu.usbmodem14201": No such file or directory
Problem uploading to board. See http://www.arduino.cc/en/Guide/Troubleshooting#upload for suggestions.

avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0x00
avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0x00
An error occurred while uploading the sketch

I've made sure that it is connected to the right port. Any idea of what could be the issue here?

Anything connected to pins 0 and 1 of the Arduino?

If so, disconnect before upload, reconnect after upload.