Error message help

I am trying to update my CR-10 and this message pops up >:(

Arduino: 1.8.10 (Mac OS X), Board: "Sanguino, ATmega1284 or ATmega1284P (16 MHz)"

Sketch uses 108226 bytes (83%) of program storage space. Maximum is 130048 bytes.
Global variables use 4535 bytes (27%) of dynamic memory, leaving 11849 bytes for local variables. Maximum is 16384 bytes.
avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0x65
avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0x63
avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0x68
avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0x6f
avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0x3a
avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0x53
avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0x44
avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0x20
avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0x69
avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0x6e
An error occurred while uploading the sketch

I have no clue how to fix it. Please help

What is a CR-10 ?

Have you got the correct COM port and board type selected in the IDE

Please supply more details of your project such as programming environment

Please read Read this before posting a programming question and follow the advice given

A CR-10 is a Creality (Brand) 3D printer that runs on marlin (software) I am sure that i have the correct port and board type Sanguino. For any missing info ask me. I am new at the arduino software so please tell me where to find the info that you might need.

On 1284 you must install the bootloader first

Here is a guide Unified 2 Firmware Archives - TH3D Studio Help Center

I did that on my cr10 mini with no problem

When the 'avrdude' program is trying to send commands to your bootloader it is receiving responses that don't match what it expects. This may be due to USB output from the printer that is sitting in the PC's input buffer. Try this:

Hold down the printer reset button.
Unplug the USB cable for several seconds.
Plug the USB cable back in.
Start the firmware upload.
When the first attempt fails, release the reset button.