Can the serial monitor be designed so that it accepts Escape codes?
If you're asking if Serial Monitor supports it, the answer is no.
If this question is a request, you should log a request on github.
My view
Serial Monitor is a debug tool and hence does not have a need for it. Use a real terminal program if you need support for ansi escape sequences.
Use a terminal emulator program such as PuTTY or Realterm. I use minicom on Linux.
...R