ESP32-S3 module or Nora-W106, Developing an embedded sensor

Hi there,
I am in the design process of an electronic board, which would use an ESP32. I think the ESP32-S3 would be the best system On chip to use, But I would rather use a module with built-in antenna, rather than developing this on my own. Now I see two different candidates:

  • espressif modules, as referenced on the ESP-Devkit development board

  • Ublox modules, NORA-W10, referenced on the arduino Nano. (I am just discovering it)

Both approach seems to have pros and cons:

The UBlox Nora-W10 would avoid me to use a UART bridge and save some space on the PCB (quite important for me). Can anyone confirm this? (in term of pricing, it seems to bring some advantage by reducing the number of filtering capacitors and assembly time)

Would i need to plan for an arduino bootloader for the NORA-W10?
I am tempted to recopy part of the schematic or the arduino NANO, with more filtering on the power rails and USB D+/D-.

If someone could clarify me these, and give me some tips, it would be very nice.