Factory Atmega 2560 unable to upload

Looks incorrect to me with SCK and MISO being swapped on your target.

(Elegoo 6 pin isp PIN numbers) (wire color) (target pin)

1 MISO -> blue -> SCK
2 5V
3 SCK -> yellow -> MISO
4 MOSI -> green -> MOSI
5 RST
6 GND

For reference: http://pighixxx.com/megapdf.pdf