Frequent calibration problem of AD 5933 for impedance measurement

Dear Sir,

I hope this message finds you well.

I am using the AD 5933 evaluation board for impedance measurement; The data sheet says it can measure the impedance up to 10M ohm. I am currently measuring the impedance of a microfluidic device, where I capture the bacteria that increase the impedance from 3M ohm to 8M ohm, which is within the range of 10M ohms. I have encountered an issue where, for instance, if the impedance measures 8M ohms and I use a 3M ohm resistor for feedback during calibration, I do not obtain the correct impedance value. However, using an 8M ohm resistor for calibration provides an accurate impedance measurement. So the problem is, every time I have to calibrate the AD 5933 if there are slight variations in the impedance value to get the correct result

I have a few questions:

  1. Is it possible to use a single resistor value as a feedback Resistor for calibration to measure impedance ranging from 1 ohm to 10M ohms, thereby overcoming the challenge of frequent calibration? If so, could you please suggest some solutions to address the issue of frequent calibration?

  2. I recently read a paper where the author utilized an HMC 245A switch to address the issue of frequent calibration in impedance measurement. Is this method effective? The HMC 245A switch is described as a non-reflective SP3T (Single Pole, Triple Throw) RF switch. In this paper, they used different resistors with an HMC 245A switch and it automatically calibrates AD 5933.

  3. Could you recommend a method, switch, or IC that if I combine it with AD 5933 and they automatically calibrate the AD 5933 and I get the correct impedance of my device from 1 ohm to 10M ohms without needing to change the feedback resistor repeatedly?

Your assistance in this matter would be greatly appreciated.

At those impedance setup is critical and any changes could be reflected in your readings. Also to measure impedance it has to pass a current through the sample, is that causing problems in your readings? Temperature of the target could possibly change readings. Can you post a picture of the setup.

Fortunately, you have at least one easy question here. The answer is: No. Please refer to the capabilities of your test device:

  • Impedance measurement range from 1 kΩ to 10 MΩ
  • Capable of measuring of 100 Ω to 1 kΩ with additional circuitry

An additional problem is this:

1 MSPS, 12-Bit Impedance Converter, Network Analyzer

1 Ohm - 10MOhm = 1:10,000,000 dynamic range. 12 bits = 1:4096 dynamic range. So if you define the range as 10MOhm max, this will make the smallest measurable step size around 2.4kOhm.

It sounds like a very good idea, indeed.

No. See above.