FTDI Port Problem

Dear Sir,

I am really need an expert advice. I am going through some serious issues hardware issue.
I am attaching my circuit diagram below.
I am getting two major problem with this

  1. I am not getting communication port without attaching battery to the circuit.
  2. Once battery got fully drain again I am not getting communication port until i de-solder and re-solder the battery again.
    Both the problem is very strange to me.

Any help will be appreciated.

Only took a brief look at the schematic. Is R9 supposed to be a pullup? Are you sure you want to use an interrupt pin for this?