Thanks for the quick reply Paul.
I've got flash covered. I'll be running it in Action Script 2. I've taken a cursory glance over the code libraries and actionscript is quite happy communicating with other programmes and the COM port.
As for your other questions: All of the LEDs will need to operate individually. The more powerful LEDs are also to operate individually, acting as spot lights within the darkened booth. They will need to provide strong white illumination of about 300-400 lumens.