All LoRa modules use a Semtech LoRa device, which is 3.3V logic.
Using 3.3V logic Arduinos is by far the easiest way to use LoRa modules and there ought to be heaps of tutorials out there for connecting to LoRaWAN.
Some companies make LoRa Shields for 5V logic Arduinos or modules that include the logic conversion stuff, eg;
Buy the right frequency band for LoRaWAN in your part of the World.