Daz1712:
Cant see it mentioned but you have run a 5v regulator into the Vin which runs to the input of a 5v onboard regulator.
>>> Run it to the 5v <<<
Actually (I) wouldn't do that.
The on-board regulator provides you with an extra layer of supply protection.
I'd rather get a clean +9-12V (nominal) into the +VIN pin, and go from there.
For the block of LEDs, I'd use a similar arrangement (bulked up to support the higher current needed)
Finally - I'd seriously look at the WS281x LED matrices. Easy to develop, and all the brains are within the actual LED chips.