Including the ATmega328PB as a further Nano variant

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Compiling with the "old" IDE type 1.8.16 gives almost the same result, only the "resp" of avrdude is different.

Sketch uses 5486 bytes (17%) of program storage space. Maximum is 32256 bytes.
Global variables use 533 bytes (26%) of dynamic memory, leaving 1515 bytes for local variables. Maximum is 2048 bytes.
C:\Users\Rudol\AppData\Local\Arduino15\packages\arduino\tools\avrdude\6.3.0-arduino18/bin/avrdude -CC:\Users\Rudol\AppData\Local\Arduino15\packages\MiniCore\hardware\avr\2.1.3/avrdude.conf -v -V -patmega328pb -carduino -PCOM3 -b115200 -D -Uflash:w:C:\Users\Rudol\AppData\Local\Temp\arduino_build_879656/ReadSignature.ino.hex:i 

avrdude: Version 6.3-20201216
         Copyright (c) 2000-2005 Brian Dean, http://www.bdmicro.com/
         Copyright (c) 2007-2014 Joerg Wunsch

         System wide configuration file is "C:\Users\Rudol\AppData\Local\Arduino15\packages\MiniCore\hardware\avr\2.1.3/avrdude.conf"

         Using Port                    : COM3
         Using Programmer              : arduino
         Overriding Baud Rate          : 115200
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0xe9
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0xe9

avrdude done.  Thank you.

Problem uploading to board.  See https://support.arduino.cc/hc/en-us/sections/360003198300 for suggestions.