Is it possible to use both the microphone and the camera simultaneously and stream their data over Wi-Fi using the ESP32-S3?

Using Arduino Networking, Protocols, and Devices
1

Please let me know how we can stream I2s mic data and camera at the same time in ESP32-S3

2

Before anyone can answer, compute the number of bytes per second that will need to be streamed.

3

That is dependent on your hardware and software you write. @Paul_KD7HB indicated you will need to know the required bandwidth you will need then determine if it is possible. At 1 bit per hour it would be a simple thing at a trillion bits a second no way. I expect you will be somewhere in the middle.