I got a chance to spend a couple of hours on the laser today so I cranked out my coarse cut of a case for a project I'm working on.
Prototyped in cardboard for concept and fit. Everything looked good so I cut it in acrylic.
I'm using a garage door opener wall wart that I can operate with the extra buttons on my fob and a RP2040 board plus an ESP-01 I have with no home.
In Phase 2 I'll post the hardware and software. I wanted to test out my interface design first.
I could post a video with it in operation
when I get it put together.
How do you avoid choking to death on the acrylic fumes? I know PVC fumes are toxic, are the acrylic fumes toxic or corrosive too? I just got an atom stack M50 5w laser. I cut some acrylic and it reeked. What are you cutting with?
Really good filter and vent system. The acrylic fumes are surely toxic but I don’t know about corrosive. I’m using a Universal Laser Systems with two 75W tubes. It has a rotary fixture so I can cut tubular stock as well but I was just using the flat table ~2’ x 4’
I’ve cut a variety of materials, acrylic, polycarbonate, HDPE, PVC, medium density foam, cardboard, cast concrete, powder coat. They all reek when you burn through them but I don’t think they are corrosive to anything but human tissue. 
Exhaust systems work pretty good but you still get some of the smoke released when you open the lid unless you wait an inordinate amount of time for it to clear.
Here's a example of a rotary fixture I designed to engrave multiple concrete pots before I cut the windows in it.

The table is aluminum and engraves well too. 