Max7219 or other to driver PC fan motor matrix

It might be made to work as you describe. And yes it would pwm the fans. But understand that, if running 64 fans with a max7219 + transistors, the maximum pwm would be 12.5%. Can you try the fans at that level? Would it be enough for whatever mysterious purpose you have in mind?

Alternatively, how about several (6~10) "Adafruit 16-Channel 12-bit PWM/Servo Driver - I2C interface - PCA9685"? You may need transistors for each channel, unless the pc fans are the type with a built-in pwm driver. I think the 4-wire type of fans are like this.