Measuring microvolt/nanovolt differences in circuit using Arduino ADC

allanhurst:
Firststep :

Re your post #36

Could you redraw your circuit to make it clear what you mean?

Allan

See Problem Statement pic. It is a long wire, where the resistance of wire on both side could be about 1k Ohm max. (around 200-400 Ohm typically). That is why I said load on both sides.

While I am still waiting for the components (yes its hard to get these things here), I have simulated your circuit design and shared the result. See pic "low Ohm measurement". But why is 0.4mV got reduced to 36.8uV? Also changing R2 isn't having any effect in the simulator.

Doing these things coz I don't want to see any magic smokes. Noticed the V+ rail attached directly to the high voltage line (50V to 400V) and V- to ground through the 22k resistor. As per the datasheet for LMC6482 and OPA192 supply voltage is 3V to 36V. Why aren't we using a 12V regular supply (the one that is powering the Arduino) to power the opamp? Just curious and precautious.

Thanks.