When trying to upload the sketch to a Mega 2560 I get the message "Problem uploading to board". I have the sketch running on one mega 2560 so I know the sketch is ok and my computer set up is working. I need to up load the sketch to a 2nd Mega 2560. Any suggestions?
Both the boards may be mega2560 but they may have different usb to serial chips, you need to tell us exactly which one you have/bought. You may have the drivers for one but not for the other.
The only thing I can find different in the two is a bar code sticker on the box. The bar code on the first one is MD0147304. The 2nd one is MD0151143. Both boards are from the same vendor ordered under the same part number about 45 days apart. I don't know how to tell what USB to serial chip they have.
Make sure you have selected the correct port from the tools -> ports menu. If no port is listed while the Arduino Mega2560 is connected, you either have driver problems, or the board is defective. Check the part number of the chip near the USB connector - if it's not a Atmel Atmega16u2, it's a clone; you will need drivers for that part (google the part number)
Assuming that is not helpful, please post the exact text of any and all error messages. You should always do this when asking for help in any case where an error message is shown.