Micro Controller software on a pc (pc as a P.I.C)

You might find something like this useful if you are trying to program a computer to interact with other hardware:

http://www.icpdas.com/root/product/solutions/pc_based_io_board/pci/pci-826lu.html

"Universal PCI, 250 kS/s, 32/16-ch 16-bit Analog Input, 2-ch 16-bit Analog Output and 32-ch Programmable DIO"

However that would be a VERY VERY expensive solution. But if you might be able to find something similar but slightly less powerful and cheaper.
EDIT: something like this:
http://accesio.com/go.cgi?p=/pci/pci_dio_24d.html
Of which their are some going cheap (~£40) on eBay at the moment.