Multiple serial connections (SPI & I2C at the same time) in Nano IOT 33

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#include <Wire.h>
#include <SPI.h>

#define Addr (0xF6>>1)
#define TASTER          3
#define LED             13
#define I2C_DEVICEID 0x00
#define I2C_POWERMODE 0x01
#define I2C_FREQUENCY 0x02
#define I2C_SHAPE 0x03
#define I2C_BOOST 0x04
#define I2C_PVOLTAGE 0x06
#define I2C_P1VOLTAGE 0x06
#define I2C_P2VOLTAGE 0x07
#define I2C_P3VOLTAGE 0x08
#define I2C_P4VOLTAGE 0x09
#define I2C_UPDATEVOLTAGE 0x0A
#define I2C_AUDIO       0x05
// pressure_sensor
int SlaveSel = 10;    //Define slave select as 10

//Transfer Variables
float Output_max   = 15099494;//for psi___counts(90% of 2^24 counts or 0xE6666)
float Output_min   = 1677722;//for psicounts (10% of 224 counts or 0x19999A)
int   P_max = 300;//for mmHg;
int   P_min = 0;
int   Byte1,Byte2,Byte3,Byte4;
float Pressure;
float Result;
unsigned long Output;
long x2;
long x1;
long x0;

int debounce = 0 ;

int mode = 0;
#define MODE_OFF  0
#define MODE_50   1
#define MODE_100  2
#define MODE_200  3
#define MODE_400  4
#define MODE_800  5
#define MODE_MAX  6

// the setup routine runs once when you press reset:
void setup() {                
  // initialize the digital pin as an output.
  Wire.begin();
  Serial.begin(9600);
  //Serial.println();
  SPI.begin(); //Begin SPI protocol
  pinMode(SlaveSel,  OUTPUT);  //Define pin 10 as an output
  
  pinMode(LED, OUTPUT);
  pinMode (TASTER,INPUT_PULLUP);
  digitalWrite(SlaveSel, HIGH);  //Pull Slave select line high

  Wire.beginTransmission(Addr);
  Wire.write(I2C_POWERMODE);             // write address = 0x01
  Wire.write(0x00); //Adress 0x01 = 0x01 (enable)
  Wire.write(0x40); // Adress 0x02 = 0x40 (100Hz)
  Wire.write(0x00); //Adress 0x03 = 0x00 (sine wave)
  Wire.write(0x00); //Adress 0x04 = 0x00 (800KHz)
  Wire.write(0x00); //Adress 0x05 = 0x00 (audio off)
  Wire.write(0x1F);                       // Adress 0x06 = 0x00 (EL1)
  Wire.write(0x1F);                       // Adress 0x07 = 0x00 (EL2)
  Wire.write(0x1F);                       // Adress 0x08 = 0x00 (EL3)
  Wire.write(0x1F);                       // Adress 0x09 = 0x00 (EL4)
  Wire.write(0x01);                       // Adress 0x0A = 0x00 (update)
  Wire.endTransmission();
}

// the loop routine runs over and over again forever:
void loop()
{
  if (digitalRead(TASTER)==LOW) {
    if (!(debounce&0x01)) {
      mode=(mode+1)%MODE_MAX;
      switch (mode) {
   case MODE_OFF:
Wire.beginTransmission(Addr);
Wire.write(I2C_POWERMODE); // start adress
Wire.write(0x00); // disable pumps
Wire.endTransmission();
digitalWrite(LED,LOW);
break;
          case MODE_50:
          Wire.beginTransmission(Addr);
          Wire.write(I2C_POWERMODE);   // start adress
          Wire.write(0x01);            // enable pumps
          Wire.write(0x00);            // frequency 50 Hz
          Wire.endTransmission();
          digitalWrite(LED,HIGH);
          break;    
        case MODE_100:
          Wire.beginTransmission(Addr);
          Wire.write(I2C_FREQUENCY);   // start adress
          Wire.write(0x40);            // 100 Hz
          Wire.endTransmission();
          break;
        case MODE_200:
          Wire.beginTransmission(Addr);
          Wire.write(I2C_FREQUENCY);   // start adress
          Wire.write(0x80);            // 200 Hz
          Wire.endTransmission();
          break;
        case MODE_400:
          Wire.beginTransmission(Addr);
          Wire.write(I2C_FREQUENCY);   // start adress
          Wire.write(0xC0);            // 400 Hz
          Wire.endTransmission();
          break;
        case MODE_800:
          Wire.beginTransmission(Addr);
          Wire.write(I2C_FREQUENCY);   // start adress
          Wire.write(0xFF);            // 800 Hz
          Wire.endTransmission();
          break;
      }
      debounce|=0x01;
    }
  } else {
    if (debounce&0x01) {
      debounce&=~0x01;
    }
  }
    SPI.beginTransaction(SPISettings(500000, MSBFIRST, SPI_MODE0)); //Begin comm with sensor while using the SPI settings: 800kHz, MSB first, SPI mode 0
 digitalWrite(SlaveSel, LOW); //Pull slave select pin low to start data transfer

Byte1 = SPI.transfer(0xAA);
delay(25);
Byte2 = SPI.transfer(0x00);
delay(25);
Byte3 = SPI.transfer(0x00);
delay(25);
Byte4 = SPI.transfer(0x00);
delay(25);

       digitalWrite(SlaveSel, HIGH);  //Pull slave select pin high to stop data transfer
       SPI.endTransaction();  //End comms with sensor
x2 = (long)Byte2<<16;
          x1 = (long)Byte3<<8;
          x0 = (long)Byte4;
          Output = x2 | x1 | x0;
           // Transfer function
           
Result = Output*5.8/15099494;
           Serial.print("mmHg");
           Serial.println(Result);

  delay(100);
}