Motors will spin the same direction if oriented in the same direction and given the same polarity. When "robot cars" are made, the "left/right" motors face opposite directions. To drive forward, one motor needs +/- while the other motor needs -/+ polarity.
The EN of all four look good in the code.
Which pin?
It looks like you have four motors.
Sounds like a wiring mistake or a power issue. If you remove the motors and use LEDs with 500ohm resistors on the Arduino pins, do you get the LEDs lighting when motor movement should occur (like the simulation shows)?