Normally, when I think about saving energy, the context is in the "Pro Mini" or bare-328P designs. Saving 14mA on a Mega2560 is just something that seems "wrong" to me.
Is a Mega2560 needed? What is the total power consumption required from the batteries?
Assuming you cannot use a Mini, have you thought about an Atmega1284? A lots of work has been done on this forum to create a stable core file for the 1284... you should investigate.
I save about 45 mA on main procesor! Glutton is the second procesor (16U2).
Yes, mega2560 is necessary, I have a lot of peripheral - sensors and a stepper motors. But this peripherals works only for a little time the board is sleeping and waiting for user requirements.
Suggestion: Use your Mega2560 as a development board to refine your software, then when you are ready to finalize your project (and save energy), move it over to a board that does not have the USB-to-serial and other power-hungry crud built in, such as: Cross Roads Electronics