No life after Uno R3

Louis
They show in the list but I get the

avrdude: stk500_getsync(): not in sync: resp=0x00

error. When I say "does not see" I mean does not communicate. This happens for the programmer as well as the boatloader.

I have been able to get the Uno R3 to program via the bootloader that it comes with but only under Arduino1.0. Arduino-1.0 also does not see any of the AvrIsp programmers

Arduino-0022 does not see anything at the moment.