No Programming via Native USB port possible on Linux

how can I stop modem-manager? I think it is running

$ ps aux | grep modem
root     14809  0.3  0.0  83412  3432 ?        S    17:00   0:00 /usr/sbin/modem-manager
lsof | grep ttyACM

returns nothing in between the 30s, where the port can not be opened.