Not possible to upload a sketch to Arduino UNO using usb

Not possible to upload a sketch to Arduino UNO using usb, anyway, at same time i can upload same sketch to an Arduino Leonardo, or even i can upload the same sketch to UNO using AVRISPMKii, i pressume that this is only a driver problem, i needed to reinstall my windows 10, after a virus, and now I’m trying to solve that, what i get on the screen:

avrdude: Version 6.3, compiled on Dec 16 2016 at 13:33:19
Copyright (c) 2000-2005 Brian Dean, http://www.bdmicro.com/
Copyright (c) 2007-2014 Joerg Wunsch

System wide configuration file is “C:\Program Files (x86)\Arduino\hardware\tools\avr/etc/avrdude.conf”

Using Port : COM10
Using Programmer : arduino
Overriding Baud Rate : 115200
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0xfc
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0xfc

avrdude done. Thank you.

Problema subiendo a la placa. Visita http://www.arduino.cc/en/Guide/Troubleshooting#upload para sugerencias.

After this: "or even i can upload the same sketch to UNO using AVRISPMKii" you have wiped out the bootloader. Re-burn the bootloader with the AVRISPMKii, and then try a download via serial port again (with programmer disconnected, it can hold reset low at times and keep the Uno looking hung)

Thanks a lot for your answer, i made it, in two diferente UNOs, i had problems in more than one, and i was replaced the bootloader several times without success, i made it once again, because you used your time to recomend it to me, and i'm totally surprised, it's working!, i need to analize the situation, because there is something i can't understand.

Thanks a lot for your help, i'm turning me crazy in the last four days rearranging my computer, and all the help is welcome.

Thanks a lot for your help.

Finally this is the driver i’m using, i don’t like it too much, but works