NRF52840 RADIO ISR Usage - Arduino Nano 33 BLE

Hello,

I am developing a custom radio protocol on the Arduino Nano 33 BLE to avoid the overhead associated with the ArduinoBLE library; however, I encountered an issue with the RADIO_IRQHandler. The handler seems to be "blocked" under the MbedOs' framework.
I noticed the following here:

I was wondering if there is a weak link to be overwritten or some way to utilize the IRQ Handler as it is imperative I have this functionality for determining when packets have been received/processed.

I have also been in communication with Nordic's team here if this helps:
https://devzone.nordicsemi.com/f/nordic-q-a/81988/using-nrf52840-radio-with-basic-custom-protocol-without-esb

Thanks!