FYI, if orange LED is on - it comes from the PMIC (power management IC). The PMIC is not properly configured, e.g. you have overwritten the bootloader.
It can happen for different reasons: for me: if I play with I2C (and one is the internal I2C bus, for PMIC access), or I have ST-LINK connected and I power cycle Portenta H7 and ST-Link (remove/connect USB) in a specific order: the orange LED comes on.
Sometime a power cycle is fine. If not: you need an external I2C master. You had to access the PMIC chip from the outside and configure it again.
If you do not have a configures PMIC: the MCU does not have voltages.
And even a debugger (external ST-LINK) would not be able to connect, e.g. in order to flash the bootloader again.
This PMIC chip on Portenta H7 causes often trouble (in combination with doing something wrong with bootloader (overwritten) or crashes in your own code.
Possible to recover - but very tricky.
And getting a bricked board - the orange LED - happens unfortunately too often.
Meanwhile, I am able to recover from it (with external tools needed: I2C master, ST-LINK debugger).