I just gave it a try and it works very well. The windows drivers / VB.NET accept 100000 baud and data transfer to and from the Arduino Uno works perfectly.
By the way does anyone know the settings for Atmel Studio 6 to integrate Avrdude? I managed to upload .hex files manually but it would of course be much more convenient to program the device directly in Atmel Studio...
Thanks for the help and suggestions so far.