when i connect wire to TX so, it's working, but, when i connect wire to RX it doesn't work.... So strange.. becouse, when i change pins (21,22) --> (22,21) , the result is the same.. only TX working...
Ambiguous. Both the ESP8266 and the UNO have pins and wires. Both the ESP8266 and the UNO can send (TX) and receive (RX) to each other. What do you mean "working"? What "doesn't work"? What do you see that tells you it doesn't work?
Please read Section 11 here.
For example, you haven't provided a circuit diagram. So I have to ask, "Are you shifting the voltage levels?" The ESP8266 is a 3.3V device. The UNO is a 5V device. The UNO voltages could damage the ESP8266.