Serial Exception Error While Uploading Code to ESP32-S3 WROOM-1

Hi everyone,
I'm working on a project using the ESP32-S3 WROOM-1 module.
When I try to upload my code through the Arduino IDE, I get a Serial Exception error during upload.
I'm not sure how to fix it, and I really need to complete this project as soon as possible.

Could someone please help me troubleshoot this issue?
Thanks a lot in advance!

A serial exception error occurred: Cannot configure port, something went wrong. Original message: OSError(22, 'The I/O operation has been aborted because of either a thread exit or an application request.', None, 995)

I moved your topic to an appropriate forum category @deepakpragadeshwar.

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Thanks in advance for your cooperation.

Hi. This typically means the serial connection is being interrupted by something, or it's not properly set up. You can try these steps:

1. Wrong/Busy COM Port

  • Check that the correct COM port is selected in Arduino IDE (ToolsPort).
  • Make sure nothing else (like another serial monitor, another Arduino IDE instance, or even some background software) is using that COM port.
  • Try disconnecting and reconnecting the ESP32-S3. See if the COM port changes.

Tip: Open Device Manager (Windows) and watch the "Ports (COM & LPT)" section when you plug and unplug the ESP32-S3 — it should appear and disappear.


2. Bad USB Cable

  • Not all USB cables are made for data! Some are charging-only cables.
  • Try a different data-capable USB cable, ideally short and good quality.

3. Driver Issues

  • Since you're on ESP32-S3, the USB interface might need a proper driver.
    Usually, it uses either:
    • Silicon Labs CP210x drivers
    • CH340 drivers
    • Or, the ESP32-S3 has built-in USB-CDC directly (no converter).

Check if you need to install or update the driver:


4. ESP32-S3 Boot Mode

  • If your ESP32-S3 doesn't enter the correct flashing mode automatically, the upload can fail.
  • Try holding down the "BOOT" button on your ESP32-S3 board while clicking Upload in Arduino IDE, and only release it when you see "Connecting...".

5. Too High Upload Speed

  • Sometimes the default upload speed (e.g., 921600 baud) is too high for a flaky cable or noisy environment.
  • Lower the upload speed:
    • In Arduino IDE → ToolsUpload Speed, try setting it to 115200 instead of 921600.

6. USB Power Issues

  • Some computers (especially laptops via hubs) don't give enough power.
  • If possible, connect directly to a rear USB port (not a hub) or try a powered USB hub.

if you have a ESP32S3 with 2 USB plugs,
use the right one ( when WIFI antenna UP )
mine is labeled 'COM' the one what makes problems is called 'USB' ( label on the back )

but on an official board the sides are switched and the labels different
left is 'UART' right is 'USB'
pls use UART

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You are correct. When i plug my data cable on left side it doesn't show that error. Thanks a lot.

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The issue is resolved. Thanks for your help.

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