'Serial port' grey out!


I have problem to upload my code, since the 'COM1' is not found! And the 'serial port' is grey out....
In device manager, I can see the Genuino Uno (COM1) when I plug in the usb which connect to the Board.

Could anyone help me address this issue?

Thank you!

Press the upload button then use the 'copy error messages' button and paste it here...

COM1 is usually not an Arduino. Does it disappear when you disconnect the board?