Hi, i can simulate the Left Click button from my Macbook with a one Button on my arduino?
It's fairly easy if your Arduino is a Leonardo model. See File->Examples->09.USB(Leonardo)->Mouse->ButtonMouseControl
For other models it's not so easy. For the UNO and Mega models you can write new firmware into the small ATmega processor used as a USB-to-Serial adapter. For other models you can use the V-USB code to bit-bang USB 1.1 with just a couple of resistors.
A third choice is to gut an old USB mouse and use the Arduino to bridge the pins for the click button.