SOLVED: ESP-01 driving me crazy.....

There's probably something wrong with your connection, or your baud rate, or both. (CIOBAUD is not permanent, IIRC, and you have to swap RX and TX.)

But most of all: AT commands are garbage. Throw out the UNO, connect the DHT22 to the ESP, and program it directly.

A Beginner's Guide to the ESP8266

Pieter