My understanding is that you have a wired serial solution.
I should explain why I cannot use the serial solution at this time. Having my Nano connected/powered by a PC provides an invasive element to a sensitive power monitoring setup. To avoid any voltage leakage into the circuit, I need to have my Mac disconnected from the Nano.
I would think that there might be a simple solution using classic bluetooth with an HC05 on the Arduino and a BT dongle on the PC if it doesn't have built in classic bluetooth.
My PC should have classic BT. Is there an existing interface/library I can use on the Nano for classic bluetooth?