Sync error, tested rx/tx

So I have a home made arduino that I am using for a project. I have had no issues on my work PC but as soon as i connect the device on my home PC and try to upload I get the following errors.

Arduino: 1.6.9 Hourly Build 2016/03/25 02:33 (Windows 10), Board: "Arduino/Genuino Uno"

Sketch uses 1,066 bytes (3%) of program storage space. Maximum is 32,256 bytes.
Global variables use 9 bytes (0%) of dynamic memory, leaving 2,039 bytes for local variables. Maximum is 2,048 bytes.
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0xd1
avrdude: stk500_recv(): programmer is not responding
avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0xd1
Problem uploading to board. See http://www.arduino.cc/en/Guide/Troubleshooting#upload for suggestions.

This report would have more information with
"Show verbose output during compilation"
option enabled in File -> Preferences.

I have tested my USB to TTL adaptor by connected the RX and TX together and insuring i am getting the data back when I hit a key, I have tried using the reset button after the compile for varrying amount of times. I have redone all of the wiring and I have checked that I have the correct board and com port selected. I have tried changing the com port to com port 1, I have tried uninstalling the com port and reinstalling, I have tried a couple of different micro controllers with the boot loader installed and lastly I have tried an older version of aruino. I went all the way back to 1.0 and tried to upload a blink program. Any ideas on where to go from here?