TX and RX indicators

During an upload of a sketch on the Arduino UNO, the TX and RX indicators are unresponsive. Is there a way to bypass or is my UNO kaput?
I've hit the reset button, used different cables, etc.
All suggestions are appreciated.

Does the upload work? If not, the USB/Serial chip is likely dead.
Does the Uno otherwise run whatever sketch you last downloaded?

The last upload will run. Newer sketches cannot be uploaded.
If the TX and RX are fried, is the processor platform beyond repair?

If the TX and RX are fried, is the processor platform beyond repair?

No it is probably not the main processor but the one that does the USB to serial conversion.
What did you do to it? That might give us a clue.

If the computer recognises the board, that is it appears in the menu, then that bit is working and you might have to re burn the bootloader in the main processor. If not you might have to reload the code in the USB / serial chip.

I can't say what happened. This processor was being used by a student, who after running a sketch did a couple of adjustments to the program and tried to upload. This is when the upload failed.
Is reloading the bootloader a common event? This processor and the others that I have are used by different groups of students.

Is reloading the bootloader a common event?

No, but it is not unheard of.

So is the board recognised by the computer?