Unable to upload to arduino Nano on new pc

HI,
i'm trying to upload a program on to my Arduino Nano on a new PC. I've checked everything I can think of.
Anyone eny ideas

Arduino: 1.8.8 (Windows 10), Board: "Arduino Nano, ATmega328P"

Sketch uses 3112 bytes (10%) of program storage space. Maximum is 30720 bytes.
Global variables use 277 bytes (13%) of dynamic memory, leaving 1771 bytes for local variables. Maximum is 2048 bytes.
avrdude: ser_open(): can't open device "\.\COM3": Access is denied.

Problem uploading to board. See http://www.arduino.cc/en/Guide/Troubleshooting#upload for suggestions.

This report would have more information with
"Show verbose output during compilation"
option enabled in File -> Preferences.

The most typical solution: Select "Old Bootloader" in the Tools | Processor: "Atmega328P" menu.

I've tried that unfortunately it doesn't make any difference