Unknown USB Device (Device Descriptor Request Failed)

Unknown USB Device (Device Descriptor Request Failed)
I keep on loosing my ItsyBitsy
They are turned int an OTP'
I can only program them once, afther that they are rejected by windows
What to do?
In Arduino->tool-> I can select board "Adafruit ItsyBitsy 32u4 3v 8MHz"
In Arduino->tool-> I can select Port
But when to select Programmer, I do not know what to select.
It is could be a boot-loader problem, occurringduring upload, I do not know.
In the preference:
https://adafruit.github.io/arduino-board-index/package_adafruit_index.json
is selected.

please help

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