UNO R3 application board

The Arduino Uno R3 PCB situation is PC can find the board USB-Serial port after using Atmel Flip to upload the USB-serial firmware . Also, I have installed the bootloader to Atmaga328. The board doesn’t accept the command from the Arduino IDE, I assume the board schematic has issue. The Error message is:

Sketch uses 13174 bytes (40%) of program storage space. Maximum is 32256 bytes.

Global variables use 1115 bytes (54%) of dynamic memory, leaving 933 bytes for local variables. Maximum is 2048 bytes.

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 1 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 2 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 3 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 4 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 5 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0x45

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0x45

Failed uploading: uploading error: exit status 1