Uno wont accept upload- what does this error mean?

I cant get started with my Nano 328mega v3.0.
Green light comes when plugged into USB port.
Nano USB connection shows up on my PC (Win7) when I run the IDE.
Nano board selected in IDE.
I try to upload simple 'Blink' programme..says 'uploading done', but error message below says 'avrdude_stk500_getsync() : not in sync resp =0x00'.
Blink programme does not run on Nano.
Pressing 'reset' button does nothing.

Any ideas please for complete newby?

You might have an old program in the Nano flooding the USB buffers. Try this:

Hold down the Reset button on the Nano.
Unplug the USB cable and plug it back in.
Click on the Upload button.
When you see the message "Binary sketch size:" release the Reset button

Thanks for the tip but it did not work, I tried it a couple of times but get the same error message. I think I may have bricked it now as the processor is getting hot and the 5V rail measures 4.55v.