Thank you Bill,
I am not familiar to level shifters, is it this one?:
If the LCD is 5v, will it work if I turn it's power down to 3v ?
I can give it 3.3v from the esp, I don't need to step down the power with a converter.
The relay is connected to the same USB port 5v, so that may also be the problem, and when I move the dupont cables connected to I2C, the screen turns on, off, and flicker, like the wires are no bueno.
May this be the issue?