Upload issue

My Arduino sketches will not upload no matter what I try. I'm running windows 10 and have the latest Arduino update, heres the error code:

"Arduino/Genuino Uno"

Sketch uses 1,144 bytes (3%) of program storage space. Maximum is 32,256 bytes.

Global variables use 15 bytes (0%) of dynamic memory, leaving 2,033 bytes for local variables. Maximum is 2,048 bytes.

avrdude: ser_open(): can't open device "\.\COM1": The system cannot find the file specified.

PLEASE HELP!

Try reading my response here: https://forum.arduino.cc/index.php?topic=359650.0

Thanks Frit, so I went to device manager headed over to my port settings and re-selected it, didn't work...