Upload issues with windows 8.1 pro 64 bit

I get "avrdude: stk500_recv(): programmer is not responding", AND Before that, "avrdude: ser_open(): can't open device "\.\COM1": Access is denied." also is displayed. And on my pc, it appears as, "FT232R USB UART" (it's an OSEPP Clone) And... it doesn't appear under "COM" (com1). Instead, it appears as "Port_#0001.Hub_#0001" for the (com port?) port.

ANY Info would be Extremely helpful.

I have exactly the same problem: here my configuration
Windows 8.1 64
Arduino nano
Arduino IDE 1.5.8

I have can’t open device “\.\COM1”: Access is denied when i try to program

Before all working fine (August/September 2014), and with Arduino uno all is today OK

I tried old and new ftdi driver,
I tried to start Arduino EDI as administrator
I tried to change the number of the port, the speed of the port
I tried to stop the anti virus

I can not use my nano board.

Please if someone have a solution :’(

Regards