Do not post screenshots of error messages unless there is some reason that text is not sufficient. The IDE even has a "copy error messages" button to make it super easy to copy the error messages to paste into your post. This is much easier for people helping you than the screenshot (particularly with this forum's boneheaded handling of attachments), and unlike the screenshot, it's searchable too.
That's not a typical error from damaged board (usually those just don't detect at all), nor a typical upload issue from something on the Arduino side of the serial adapter (those result in sync errors)
Is the correct port selected? Selecting something that doesn't correspond to the board you want to talk to can do this.
Are the drivers installed correctly? Missing/unhappy drivers can cause this.
Is another application trying to use the same port at the same time? That could also (I think) cause this issue.
Have you rebooted computer since you started getting that error?
Did it work in the past? If so, what changed?