Uploading problem in my Arduino

Thanks for the reply.
Before sending the message to you yesterday, I had already removed the customised circuit and connected only the Arduino UNO which works well with Blink sketch preloaded.
Uploading problem occurs even with this as mentioned in the message. And I had made observations as mentioned in the yesterday's message.

Thanks for response.
I wait for your reply sir.
Thanks and regards.

SUBRAMANYA