Using the USB connection on Mega 2560 for serial input?

I want to use TouchDesigner ( to output serial data to the Arduino plugged into the computer via it possible to read serial input from the USB connection on the Arduino? This may be a basic question but I'm pretty noob-ish to this platform...any help would be greatly appreciated!

Yes you can. Add Serial.begin(9600); or some speed into void setup, and then do not use D0/D1 in your sketch.

Thanks CrossRoads!