wellness wristand help

Hello all,
I'm helping a youth group to make a project involves monitoring elderly stress.

The idea is based on a wristband with some sensors (gsr, pulse, breath) & microphone & communication

I'd like to be able to analyze sensors in real-time, and if some thresholds exceed, stream microphone audio to mobile app over BLE , WIFI, GSM (whatever is easier).

The package should be small enough to fit somehow on a large wristband.

Do you think that Arduino Nano can handle such task ?
Also, what about Wino board - https://wino-board.com/ ?
Or , what do you think of beetle with BLE ? (Beetle BLE - The Smallest Board Based on Arduino Uno with Bluetooth 4.0 - DFRobot)

Will be happy for reccomendation of GSR sensor that can be embed in a wristband.
and a pulse/ heartbeat sensor

thank you