Wemos and arduino software serial

Hi,

Is it possible to establish serial communication form wemos(or any esp8266 microcontroller) to arduino uno using Software serial ?

Yes but be aware SoftwareSerial cannot handle high baud rates like the esp8266 can and depending on what Arduino your connecting, you may need to do voltage level shifting of the Arduino TX pin as the esp8266 is only 3.3v and your Arduino might be 5V.