Which Arduino Board to use??

Can i use arduino mega 2560??

No. The 2560 is not a 386.

Actually Sir i am making a device(with a touch screen) which sort of based on a mechanism that it
takes data from a device at one port and transfers it to a device at another port..please help me out.
how to start.
Can arduino uno supports this??

Your specification has insufficient information for me to make a guess. You will have to be much more specific if you want an answer.