Your upgrades should not change anything in relationship to the Arduino so it should be safe to discount those.
That you installed those other drivers will not harm either and may prove useful if you get a clone so we can rule those out too.
Lets step back a little bit as you should be able to see something in device manager.
Here is a screenshot from my win 10 box.
You should be seeing something under com & lpt ports.
If you dont see a UNO in the comport section or a device with an error at the very least. its almost safe to assume there is a major problem with the board