The I2c library is faster than the wire library. The values presented in the table are code-size in bytes and duration of whatever write read function. The calculation you did assumes that the first number given is the number of bytes transferred per time, which, again , is not what the numbers represent.
The I2C signals are realized in hardware, thus the likelyhood that your application will have to wait because of the " blocking" behavior is very small. Removing dependence on interrupts makes this library more flexible to use as it eliminates its chance of interfering with other libraries that may also want to use the same interrupts.
The reason this library worked better for me was because of the timeout and reset, a function the wire library does it offer, or at least did not when I write the software for my prject.